Details of the Target
General Information of Target
| Target ID | LDTP17532 | |||||
|---|---|---|---|---|---|---|
| Target Name | MAM domain-containing protein 2 (MAMDC2) | |||||
| Gene Name | MAMDC2 | |||||
| Gene ID | 256691 | |||||
| Synonyms |
MAM domain-containing protein 2; MAM domain-containing proteoglycan; Mamcan |
|||||
| 3D Structure | ||||||
| Sequence |
MATGEHTPDDPLLRGKRRQDLQEMLREVGLDVEYWLPKLQEHLGVTCAQALQHLDKNNLK
KLKSQTQHPWEKLLNLSHSKSLSALLQESQVERAKRKQKQAEQALQELRDLLTEGKQRQE EAVRTREAELRQAMDIPEEYWPSPEEPLRELMENLQRQLNLMKWTLCHRQNLPDRDVVRW ASGGLALQGIYKASHQRGLTEKREELLSVPKEFLLLGPQQGTQMKTKEFTSPQAEFMFTQ MVEKLGFRLTTSAKDGNWGFSLEAGLDHSKHPESKETQQSSSENSYFCSTKFSYIPLASC HFPIDQLQLSKPAVQELKCIEELLSQTTNPDRFSLLRHRIINFFHRFGSHVNQGPLHLGG IYWWKAISEGYCTEQLAEVRQQSAEALDIFIRDSYSGFGVKVAAGVNVSDSHSKTATQTK TSQNLQTKVQLSVAQTGGPPEADGLVQWKAGLIASNQTWCVIDRGLQLVPVWDIILSSHR SNFKDPLQVANFLKDSYTALTSITAQIQNGEELLSAGKEARVFLEDVKSWEVSDPEEQLK KLINFMKMLSQKLKSYDTWINICLTDSLQNFLVNTINFCKKSSIYKTKCIKSHLRSLLDP HIYRVTNFPQAHFIMQWIFQSDSEQEQVNISQFSQLIEILKETQNNLMEVKVKSESPETV EEAQRKSTYEVSLALSCFLNYLQKTEQTDTQLLLLSIAAAAGYHVINNTFQSLLGCDELS FLLDEMQTAQNKYQELKNICSYRAQAFLVLTGLTATVGDTAISSEEKTQRMSLMRHHMGQ SLSKEVAHVLTKPGADHDWENLEKDLRLLINGDYEEVTISSLQMEEVSKQSLFYGKKQPH EPHDNENNKWEMIKNGAFLDLLQHLGLEHYYPKKLSKANFHLIYKTSVYNTQPSSEQELP FYFLQKLLMMDYELRYLVFKDDRNTEHQVHPNASDQEDEAFDPYENFFEDSDSPTKSSST EPSPHIHPVDIQMTIFHCADNFARQYILAKLSTCQFALPLLVPNPCTSQIEFSLWSLRQI TRSWQEARKSPKGKNYYKNQQMCCVSTSIVSFVRVGNGLSASKSQIMNCLLSKRKHDVFF HRHCTGSRKDCLLMGGMVEICWFCPGGEDEDRFDNCVTFTNLHGDAKEHEQQLSFLKEVS TVIVVLMSASDDNEGNRKIVRNLWQSSRPLICLLDDKEATMTNISGQRMRMGIKNRNEAE LTEELTTTIRHLLELSDTALSLEDCSQIAHQQGFLIDEDQRDCKEAKEKAQALMAFLGKM KLSQIKEKLLPLQGQLWHHWCKKDKELYHLREKGNQSIEQHKSEIETDKQIIRHEQLARA LPLNDLMQSVLQFLQEHSEIHTKLYFLQWLSVFLDKLTAGHLEELHEKQKYWWSLVQTVK QKAPNSHSLICLQSEIEAISTEISDCTLGIEQLIREVGQIYEALEEASSIKKIFFSLPQI AADLMISGVPIELMDGDAAYVPLTWVAAVFDKVSEKLGDKRLFVLSILGLQSSGKSTVLN ALFGLQFTVSAGKCTQGAYMQLLKVEETFTEELGFDFVLAVDTEGLRAPEHSNKSKDRDN ELVTFVIGLANLTLINIFGENPSEMQDILQIVVQAFLRMKQVKIFPSCLFVHQNVGEATA TDQTMDGRRRLEQKLDEMAAIAAEQEQCLDVTCFSDVIRFDVNTHVYYFAHLWDGNPPMA PPNPRYSHNVQQLKSRILMTATQESRGNIMKISDVKSRVQDLWRGLMNENFIFSFRNTQE VMAMNKLETMYNHWTWELRSHVLGLQNQLINQIQNGKIQTLEASTFEVLVTEKYEVVKQE LEKYFNEGPCSKILIQCKANFENKLIVLKEKLISDSKRQANELISFKNQSQERLNKKKTD YEKELLEKSRKLALTVKGKELSEEELHEKFNQLWKKWVCDVSTTLPQVTEPDIDLDSENI LWEYFKNKTNVVGLLTNSAEKFQINYDKHIKVNKKYNHIPMTLTVFEKEFINMTTDYIVS RFNKIINNMWKQQCGYNPNYFHEILKTIEEEVKSASTQKRYTFTNTFIIDLCVCLFQRAR ENFKEMHRAFKRANDPVNYLESKKDDFFTSFKISCQGATSIKTFVDVLWYKLTPAVSTTI WEDMTFKIAGDMRATCPAFNGNRTNLEKHILFSLAEEENFDNYWEYLHNSKSFFRSYIKN HIKRYCSDNGGEKMKTFFEKSLIDIKNTILSAIHESTSVAKDKSSTASEWLDLFCDCLGC NLIFPRRDLISIEHQEIKHTEFLKEAMSAALDLTMKKIEQNYSSKPIEAMVSKIEKMLSE HLCGCWKQCPSCGAICTNTIPTHEGDHSVPFHRPQAVNGEEWYETDDFVIDCCTSLVASD CLLVLRDGRNFPFKNYRQAGGDYAMWSITPDTSIQLYWKWFVSHFRSNLEEKYQKKFAGK GKIPNAWAKITKQDVLEDLKKQ |
|||||
| Target Bioclass |
Other
|
|||||
| Subcellular location |
Secreted, extracellular space, extracellular matrix
|
|||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C475(2.13) | LDD2253 | [1] | |
Competitor(s) Related to This Target