Details of the Target

General Information of Target

Target ID LDTP17508
Target Name Small integral membrane protein 5 (SMIM5)
Gene Name SMIM5
Gene ID 643008
Synonyms
C17orf109; Small integral membrane protein 5
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAKWGQGNPHWIVEEREDGTNVNNWRWTERDATSLSKGKFQELLVGIVVENDAGRGEINE
LKQVEGEASCSSRKGKLIFFYEWNIKLGWKGIVKESGVKHKGLIEIPNLSEENEVDDTEV
SLSKKKGDGVILKDLMKTAGTAKVREALGDYLKALKTEFTTGMILPTKAMATQELTVKRK
LSGNTLQVQASSPVALGVRIPTVALHMMELFDTTVEQLYSIFTVKELTNKKIIMKWRCGN
WPEEHYAMVALNFVPTLGQTELQLKEFLSICKEENMKFCWQKQHFEEIKGSLQLTPLNG
Target Bioclass
Other
Subcellular location
Membrane
Uniprot ID
Q71RC9
Ensemble ID
ENST00000375215.3
HGNC ID
HGNC:40030

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C129(0.00); C295(0.00)  LDD0161  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Peroxisomal bifunctional enzyme (EHHADH) Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase family Q08426
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Proline-rich transmembrane protein 2 (PRRT2) CD225/Dispanin family Q7Z6L0
Endophilin-B1 (SH3GLB1) Endophilin family Q9Y371
Other
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Putative ribosome-binding factor A, mitochondrial (RBFA) RbfA family Q8N0V3
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) SGT family O43765
Arfaptin-1 (ARFIP1) . P53367
Zinc finger FYVE domain-containing protein 21 (ZFYVE21) . Q9BQ24

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060