Details of the Target

General Information of Target

Target ID LDTP17463
Target Name Zinc finger protein 841 (ZNF841)
Gene Name ZNF841
Gene ID 284371
Synonyms
Zinc finger protein 841
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MIEYQIPVSFKDVVVGFTQEEWHRLSPAQRALYRDVMLETYSNLVSVGYEGTKPDVILRL
EQEEAPWIGEAACPGCHCWEDIWRVNIQRKRRQDMLLRPGAAISKKTLPKEKSCEYNKFG
KISLLSTDLFSSIQSPSNWNPCGKNLNHNLDLIGFKRNCAKKQDECYAYGKLLQRINHGR
RPNGEKPRGCSHCEKAFTQNPALMYKPAVSDSLLYKRKRVPPTEKPHVCSECGKAFCYKS
EFIRHQRSHTGEKPYGCTDCGKAFSHKSTLIKHQRIHTGVRPFECFFCGKAFTQKSHRTE
HQRTHTGERPFVCSECGKSFGEKSYLNVHRKMHTGERPYRCRECGKSFSQKSCLNKHWRT
HTGEKPYGCNECGKAFYQKPNLSRHQKIHARKNAYRNENLIIVGNT
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q6ZN19
Ensemble ID
ENST00000389534.8
HGNC ID
HGNC:27611

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C25(3.69)  LDD3419  [1]
HHS-465
 Probe Info  		K255(0.00); K258(0.00); Y257(0.00)  LDD2240  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 G-361 C25(2.58)  LDD2329  [1]
 LDCM0023  KB03 G-361 C25(4.14)  LDD2746  [1]
 LDCM0024  KB05 SH-4 C25(3.69)  LDD3419  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010