Details of the Target

General Information of Target

Target ID LDTP17329
Target Name Schlafen family member 12-like (SLFN12L)
Gene Name SLFN12L
Gene ID 100506736
Synonyms
SLFN5; Schlafen family member 12-like
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MAKSFPVFSLLSFILIHLVLSSVSGPRHWWPPRGIIKVKCPYEKVNLSWYNGTVNPCPGL
YQPICGTNFITYDNPCILCVESLKSHGRIRFYHDGKC
Target Bioclass
Enzyme
Family
Schlafen family
Subcellular location
Membrane
Uniprot ID
Q6IEE8
HGNC ID
HGNC:33920

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C622(2.32)  LDD3310  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 697 C622(1.69)  LDD2245  [1]
 LDCM0023  KB03 697 C622(3.98)  LDD2662  [1]
 LDCM0024  KB05 COLO792 C622(2.32)  LDD3310  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840