Details of the Target
General Information of Target
| Target ID | LDTP17260 | |||||
|---|---|---|---|---|---|---|
| Target Name | Zinc finger protein 468 (ZNF468) | |||||
| Gene Name | ZNF468 | |||||
| Gene ID | 90333 | |||||
| Synonyms |
Zinc finger protein 468 |
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| 3D Structure | ||||||
| Sequence |
MQPSPPPTELVPSERAVVLLSCALSALGSGLLVATHALWPDLRSRARRLLLFLSLADLLS
AASYFYGVLQNFAGPSWDCVLQGALSTFANTSSFFWTVAIALYLYLSIVRAARGPRTDRL LWAFHVVSWGVPLVITVAAVALKKIGYDASDVSVGWCWIDLEAKDHVLWMLLTGKLWEML AYVLLPLLYLLVRKHINRAHTALSEYRPILSQEHRLLRHSSMADKKLVLIPLIFIGLRVW STVRFVLTLCGSPAVQTPVLVVLHGIGNTFQGGANCIMFVLCTRAVRTRLFSLCCCCCSS QPPTKSPAGTPKAPAPSKPGESQESQGTPGELPST |
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| Target Bioclass |
Transcription factor
|
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| Family |
Krueppel C2H2-type zinc-finger protein family
|
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| Subcellular location |
Nucleus
|
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| Function | May be involved in transcriptional regulation. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
| Cell line | Mutation details | Probe for labeling this protein in this cell | |||
|---|---|---|---|---|---|
| COLO792 | SNV: p.P4S | . | |||
| HCC15 | SNV: p.G295V | DBIA Probe Info | |||
| IGROV1 | Deletion: p.K232NfsTer4 | DBIA Probe Info | |||
| KMCH1 | SNV: p.Q5K | DBIA Probe Info | |||
| MFE319 | SNV: p.G64D | . | |||
| NCIH2286 | SNV: p.C329Y | . | |||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C62(3.27) | LDD3311 | [1] | |
|
IA-alkyne Probe Info |
 |
C264(0.00); C273(0.00) | LDD0167 | [2] | |
|
HHS-465 Probe Info |
 |
K325(0.00); K328(0.00); K381(0.00); K384(0.00) | LDD2240 | [3] | |
Competitor(s) Related to This Target
References