Details of the Target
General Information of Target
| Target ID | LDTP17249 | |||||
|---|---|---|---|---|---|---|
| Target Name | Rho GTPase-activating protein 40 (ARHGAP40) | |||||
| Gene Name | ARHGAP40 | |||||
| Synonyms |
C20orf95; Rho GTPase-activating protein 40; Rho-type GTPase-activating protein 40 |
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| 3D Structure | ||||||
| Sequence |
MAGAEPFLADGNQELFPCEVCGRRFAADVLERHGPICKKLFNRKRKPFSSLKQRLQGTDI
PTVKKTPQSKSPPVRKSNWRQQHEDFINAIRSAKQCMLAIKEGRPLPPPPPPSLNPDYIQ RPYCMRRFNESAAERHTNFCKDQSSRRVFNPAQTAAKLASRAQGRAQMGPKKEPTVTSAV GALLQNRVLVATNEVPTKSGLAMDPASGAKLRQGFSKSSKKD |
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| Target Bioclass |
Other
|
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| Function | GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
IPM Probe Info |
 |
C298(8.89) | LDD2229 | [1] | |
|
W1 Probe Info |
 |
K232(0.00); D229(0.00); R231(0.00) | LDD0236 | [2] | |
References