Details of the Target

General Information of Target

Target ID LDTP17242
Target Name Dynein axonemal assembly factor 9 (DNAAF9)
Gene Name DNAAF9
Gene ID 25943
Synonyms
C20orf194; Dynein axonemal assembly factor 9; DNAAF9
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MQPAERSRVPRIDPYGFERPEDFDDAAYEKFFSSYLVTLTRRAIKWSRLLQGGGVPRSRT
VKRYVRKGVPLEHRARVWMVLSGAQAQMDQNPGYYHQLLQGERNPRLEDAIRTDLNRTFP
DNVKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLILITNNEEESFWLLDA
LVGRILPDYYSPAMLGLKTDQEVLGELVRAKLPAVGALMERLGVLWTLLVSRWFICLFVD
ILPVETVLRIWDCLFNEGSKIIFRVALTLIKQHQELILEATSVPDICDKFKQITKGSFVM
ECHTFMQKIFSEPGSLSMATVAKLRESCRARLLAQG
Target Bioclass
Other
Function May act as an effector for ARL3.
Uniprot ID
Q5TEA3
Ensemble ID
ENST00000252032.10
HGNC ID
HGNC:17721

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C29(0.83)  LDD3424  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 Hep-G2 C29(2.14)  LDD2354  [1]
 LDCM0023  KB03 Hep 3B2.1-7 C29(1.74)  LDD2770  [1]
 LDCM0024  KB05 SK-HEP1 C29(0.83)  LDD3424  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840