Details of the Target

General Information of Target

Target ID LDTP17210
Target Name Transmembrane protein 240 (TMEM240)
Gene Name TMEM240
Gene ID 339453
Synonyms
C1orf70; Transmembrane protein 240
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGSQGSGGVPLVQAPYTVLLLPLGTSRQDPGAQSFFLWLRRMQALEREQDALWQGLELLQ
HGQAWFEDHLREAQRQQLHLGALGENFLTDLHSEPGRPPLAQIQKVNICLQNLIHEKELS
RQQKGVTQPKEEMAQRGCTKGPRGPTRV
Target Bioclass
Other
Family
TMEM240 family
Subcellular location
Synapse
Uniprot ID
Q5SV17
Ensemble ID
ENST00000378733.9
HGNC ID
HGNC:25186

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Acrolein
 Probe Info  		N.A.  LDD0217  [1]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [1]
Methacrolein
 Probe Info  		N.A.  LDD0218  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [1]
 LDCM0107  IAA HeLa N.A.  LDD0221  [1]
 LDCM0109  NEM HeLa N.A.  LDD0223  [1]

References

1 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.