Details of the Target

General Information of Target

Target ID LDTP17195
Target Name Zinc finger protein 484 (ZNF484)
Gene Name ZNF484
Gene ID 83744
Synonyms
Zinc finger protein 484
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSGHQRTRSRSRERRDDQDSNHPVGAVVAQELPSNDQLQQEEPPIESQDYTPGQERDEGA
LDFQVLGLAAYLWELTRSKTGGERGDGPNVKGEFLPNLEPVKIPEAGEGQPSV
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q5JVG2
Ensemble ID
ENST00000332591.6
HGNC ID
HGNC:23385

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
COLO792 SNV: p.E357K .
HT115 SNV: p.I721T .
KMRC1 SNV: p.D255H .
MEC1 SNV: p.T618I .
NCIH1993 SNV: p.S216F .
SNGM SNV: p.A148S .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HHS-465
 Probe Info  		K522(0.00); K525(0.00); Y524(0.00)  LDD2240  [1]

References

1 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010