Details of the Target

General Information of Target

Target ID LDTP17186
Target Name Protein FAM47A (FAM47A)
Gene Name FAM47A
Gene ID 158724
Synonyms
Protein FAM47A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGNYLLRKLSCLGENQKKPKKGNPDEERKRQEMTTFERKLQDQDKKSQEVSSTSNQENEN
GSGSEEVCYTVINHIPHQRSSLSSNDDGYENIDSLTRKVRQFRERSETEYALLRTSVSRP
CSCTHEHDYEVVFPH
Target Bioclass
Other
Family
FAM47 family
Uniprot ID
Q5JRC9
Ensemble ID
ENST00000346193.5
HGNC ID
HGNC:29962

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		N.A.  LDD0241  [1]
DBIA
 Probe Info  		C650(2.40)  LDD3439  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 ECC2 C650(2.52)  LDD2320  [2]
 LDCM0023  KB03 ECC2 C650(2.62)  LDD2737  [2]
 LDCM0024  KB05 SNU-1196 C650(2.40)  LDD3439  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cytoplasmic protein NCK2 (NCK2) . O43639

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840