General Information of Target

Target ID LDTP17150
Target Name Uncharacterized protein C4orf17 (C4orf17)
Gene Name C4orf17
Gene ID 84103
Synonyms
Uncharacterized protein C4orf17
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL
CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA
DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS
LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF
SREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLE
RLDKEFYEEEERAEADVIRQRLKEEKEQEPEPQRDLEPEQSLI
Target Bioclass
Other
Uniprot ID
Q53FE4
Ensemble ID
ENST00000326581.9
HGNC ID
HGNC:25274

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HEC1B SNV: p.Q67K .
MCC13 SNV: p.I49V .
MDST8 SNV: p.Q90L .
NCIH1793 SNV: p.W213Ter .
RKO SNV: p.G274V .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info 
C334(0.00); C235(0.00); C198(0.00)  LDD0161  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
LON peptidase N-terminal domain and RING finger protein 1 (LONRF1) . Q17RB8
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Zinc finger protein 417 (ZNF417) Krueppel C2H2-type zinc-finger protein family Q8TAU3
Other
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Progranulin (GRN) Granulin family P28799
Homer protein homolog 3 (HOMER3) Homer family Q9NSC5
Cytoplasmic protein NCK2 (NCK2) . O43639

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060