General Information of Target

Target ID LDTP17116
Target Name Annexin-2 receptor (ANXA2R)
Gene Name ANXA2R
Gene ID 389289
Synonyms
AX2R; C5orf39; Annexin-2 receptor; Annexin II receptor; AXIIR
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MELLTFKDVAIEFSPEEWKCLDTSQQNLYRDVMLENYRNLVSLGVSISNPDLVTSLEQRK
EPYNLKIHETAARPPAVCSHFTQNLWTVQGIEDSFHKLIPKGHEKRGHENLRKTCKSINE
CKVQKGGYNRINQCLLTTQKKTIQSNICVKVFHKFSNSNKDKIRYTGDKTFKCKECGKSF
HVLSRLTQHKRIHTGENPYTCEECGKAFNWSSILTKHKRIHAREKFYKCEECGKGFTRSS
HLTKHKRIHTGEKPYICEKCGKAFNQSSTLNLHKRIHSAQKYYKCEECGKAFKWSSSLNE
HKRIHAGEKPFSCEECGNVFTTSSDFAKHKRIHTGEKPYKCEECGKSFNRSTTLTTHKRI
HTGEKPYTCEECGKAFNWSSTLNVHKRIHSGKNPYKCEDCGKAFKVFANLHNHKKIHTGE
KPYICKQCGKAFKQSSHLNKHKKIHTVDKPYKCKECGKAFKQYSNLPQHKRTHTGGKF
Target Type
Literature-reported
Target Bioclass
Other
Function May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation.
TTD ID
T80966
Uniprot ID
Q3ZCQ2
DrugMap ID
TTM7D9O
Ensemble ID
ENST00000314890.3
HGNC ID
HGNC:33463

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info 
N.A.  LDD0161  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
CCR4-NOT transcription complex subunit 1 (CNOT1) CNOT1 family A5YKK6

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060