Details of the Target

General Information of Target

Target ID LDTP17113
Target Name Zinc finger protein 528 (ZNF528)
Gene Name ZNF528
Gene ID 84436
Synonyms
KIAA1827; Zinc finger protein 528
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPAGSMSTTGYPGVCSTTSYRTHCYIPVTSSVTLSSSDLSPTFGHCLPSSYQGNLWLLDY
CQESYGEAPTCKSPSCEPKTCSTTGCDPSNSSVPCNSPSAGQVFSVCETTNVSPSPSCSP
STQTNGYVCNCHIPTRNASKACQTLRNGSNCFGQLNCLSKSFQTLNHCRLSTLGYKSYQN
PCFIPSYVSPLCYISNSCQPQSYLVRNYHYSSYRPTSCRPLSYLSRSFRSLSYIPSTFPP
LRYLCSGSRPLKCY
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q3MIS6
Ensemble ID
ENST00000360465.8
HGNC ID
HGNC:29384

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HT115 SNV: p.R261I .
KMS27 SNV: p.L32F .
MDAMB468 SNV: p.N531H .
MFE319 SNV: p.I15T .
OCUM1 SNV: p.Q114E .
SHP77 SNV: p.V221F .
SKN SNV: p.D26G .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HHS-465
 Probe Info  		K267(0.00); K270(0.00); Y269(0.00)  LDD2240  [1]

References

1 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010