Details of the Target

General Information of Target

Target ID LDTP17103
Target Name Zinc finger protein SNAI3 (SNAI3)
Gene Name SNAI3
Gene ID 333929
Synonyms
ZNF293; Zinc finger protein SNAI3; Protein snail homolog 3; Zinc finger protein 293
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MATLLAWVGVSCCELAEEDFLAVSPLDPRYREVHYVLLDPSCSGSGMPSRQLEDPGAGTP
SPVRLHALAGFQQRALCHALTFPSLQRLVYSMCSLCQEENEDMVPDALQQNPGAFRLAPA
LPARPHRGLSTFPGAEHCLRASPKTTLSGGFFVAVIERVEMPT
Target Bioclass
Transcription factor
Family
Snail C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function
Seems to inhibit myoblast differentiation. Transcriptional repressor of E-box-dependent transactivation of downstream myogenic bHLHs genes. Binds preferentially to the canonical E-box sequences 5'-CAGGTG-3' and 5'-CACCTG-3'.
Uniprot ID
Q3KNW1
Ensemble ID
ENST00000332281.6
HGNC ID
HGNC:18411

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C239(0.00); C242(0.00)  LDD2241  [1]

References

1 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853