Details of the Target

General Information of Target

Target ID LDTP17090
Target Name Fer-1-like protein 6 (FER1L6)
Gene Name FER1L6
Gene ID 654463
Synonyms
C8orfK23; Fer-1-like protein 6
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPKGRAGSLPTTSIGWRFQLWFLGLTCPERHLARRLKNNSFYPFVQQEPNVFVLEYYLDT
LWKGMLLFIISVVLVSFSSLREVQKQETWVFLVYGVGVGLWLVISSLPRRRLVLNHTRGV
YHFSIQGRTVCQGPLHLVYVRLALSSDAHGRCFFHLVLGGHRLEPLVLVQLSEHYEQMEY
LGRYIARKLNINYFDYLATSYRHVVRHWPPPGAGTVMGKSPMGHKPSSSQSSLEV
Target Bioclass
Other
Family
Ferlin family
Subcellular location
Membrane
Uniprot ID
Q2WGJ9
Ensemble ID
ENST00000522917.5
HGNC ID
HGNC:28065

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C1728(1.72)  LDD3338  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 Caov-3 C1728(1.43)  LDD2295  [1]
 LDCM0023  KB03 Caov-3 C1728(1.71)  LDD2712  [1]
 LDCM0024  KB05 MV4-11 C1728(1.72)  LDD3338  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840