General Information of Target

Target ID LDTP17076
Target Name Exocyst complex component 3-like protein 2 (EXOC3L2)
Gene Name EXOC3L2
Synonyms
XTP7; Exocyst complex component 3-like protein 2; HBV X-transactivated gene 7 protein; HBV XAg-transactivated protein 7
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MTARAFWLLCLIVGSSPEAPVAERKTSPPHSRKPDSRGCPSAEETPGPRAQPLLEAPQRP
RAAEVAPAARAWPDPRRRKPPPPADNQASFREAARAPAGPPGPRLAQAENRASPRREPAS
EDAPRRARSRALRFPAARPPALATEGSAGHAHPNRPRAAALAPGPAPAPPPRFSLSFGLS
PPQRDAEPGAEPCARACRSDLDEREAFCESEFAVNGIVHDVDVLGAGIRLVTLLVDRDGL
YKMNRLYLTPDGFFFRVHMLALDSSSCNKPCPEFKPGSRYIVMGHIYHKRRQLPTALLQV
LRGRLRPGDGLLRSSSSYVKRFNRKREGQIQGAIHTQCI
Target Bioclass
Other
Family
SEC6 family
Uniprot ID
Q2M3D2
HGNC ID
HGNC:30162

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C130(1.44)  LDD2324  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 EoL-1 C130(1.44)  LDD2324  [1]
 LDCM0023  KB03 HEL C130(3.66)  LDD2768  [1]
 LDCM0024  KB05 EoL-1 C130(1.34)  LDD3158  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840