Details of the Target
General Information of Target
| Target ID | LDTP17068 | |||||
|---|---|---|---|---|---|---|
| Target Name | SKI/DACH domain-containing protein 1 (SKIDA1) | |||||
| Gene Name | SKIDA1 | |||||
| Gene ID | 387640 | |||||
| Synonyms |
C10orf140; DLN1; SKI/DACH domain-containing protein 1; Protein DLN-1 |
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| 3D Structure | ||||||
| Sequence |
MAEQWELDEEGIRRLGALTLEQPELVESLSLQGSYAGKIHSIGDAFRNFKNLRSLDLSRN
LITSLKGIQYLCSLQDLNLYYNNIPSLVEVSRLQPLPFLKELDLRLNPVVRKDTDYRLFA VYTLQTLEKLDDRTVREGERKAAKLHFSQLGNSENFLLEVEKSSREKTMKNCVTGESSAS KVSANVDSRIEMDSNKGLFIPFPNREIKDSLSTSATQGNGTRDQKLDTFPLGTQTQEVAR REMPSDNHQEDEFRHYSPRQSTVRSPEKMTREGYQVSFLDNKSSGSSPEKELIPKPDTFH LTHDASLSKCLDVGDSSQIHPYQLPSDVGLENYDSCYSQTLSLHGSLGKRPQRSKNYQEY SIKPSNDIKTTASHSCGDLLTSLSNPDSSTGRLLKLSSDLYATTHFNSDPAVLVNVEQQL STSLDDLTPAHGSVPNNAVLGNRTTPLRTLLLSPGTSEHRKIFTKRSLSPSKRGFKWKDN ILANLNLKHGFQDATGSEPLSSDLGSLHGLAGNHSPPISARTPHVATVLRQLLELVDKHW NGSGSLLLNKKFLGPARDLLLSLVVPAPSQPRCCSHPEDTMKAFCRRELELKEAAQLVPN DMESLKQKLVRVLEENLILSEKIQQLEEGAAISIVSGQQSHTYDDLLHKNQQLTMQVACL NQELAQLKKLEKTVAILHESQRSLVVTNEYLLQQLNKEPKGYSGKALLPPEKGHHLGRSS PFGKSTLSSSSPVAHETGQYLIQSVLDAAPEPGL |
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| Target Bioclass |
Other
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| Family |
DACH/dachshund family
|
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
| Cell line | Mutation details | Probe for labeling this protein in this cell | |||
|---|---|---|---|---|---|
| FTC133 | SNV: p.H180Y | . | |||
| HT115 | SNV: p.A198V | . | |||
| HT1376 | SNV: p.P799Q | . | |||
| KMS11 | SNV: p.N586S | . | |||
| LS180 | SNV: p.E419D | . | |||
| MFE319 | SNV: p.A228S | . | |||
| MOLT4 | SNV: p.R99H; p.R789Ter | . | |||
| OCUG1 | SNV: p.N330H | DBIA Probe Info | |||
| PF382 | SNV: p.S268R | . | |||
| RL | SNV: p.E519A | . | |||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C219(2.53) | LDD3373 | [1] | |
Competitor(s) Related to This Target