Details of the Target

General Information of Target

Target ID LDTP17032
Target Name Mammaglobin-A (SCGB2A2)
Gene Name SCGB2A2
Gene ID 4250
Synonyms
MGB1; UGB2; Mammaglobin-A; Mammaglobin-1; Secretoglobin family 2A member 2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAAATLRTPTQGTVTFEDVAVHFSWEEWGLLDEAQRCLYRDVMLENLALLTSLDVHHQKQ
HLGEKHFRSNVGRALFVKTCTFHVSGEPSTCREVGKDFLAKLGFLHQQAAHTGEQSNSKS
DGGAISHRGKTHYNCGEHTKAFSGKHTLVQQQRTLTTERCYICSECGKSFSKSYSLNDHW
RLHTGEKPYECRECGKSFRQSSSLIQHRRVHTAVRPHECDECGKLFSNKSNLIKHRRVHT
GERPYECSECGKSFSQRSALLQHRGVHTGERPYECSECGKFFTYHSSLIKHQKVHSGSRP
YECSECGKSFSQNSSLIEHHRVHTGERPYKCSECGKSFSQRSALLQHRGVHTGERPYECS
ECGKFFPYSSSLRKHQRVHTGSRPYECSECGKSFTQNSGLIKHRRVHTGEKPYECTECGK
SFSHNSSLIKHQRIHSR
Target Type
Literature-reported
Target Bioclass
Other
Family
Secretoglobin family, Lipophilin subfamily
Subcellular location
Secreted
TTD ID
T31577
Uniprot ID
Q13296
DrugMap ID
TT1W3RE
Ensemble ID
ENST00000227918.3
HGNC ID
HGNC:7050

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
8305C SNV: p.D91Y .
FADU SNV: p.M5V .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C494(0.00); C339(0.00); C160(0.00); C76(0.00)  LDD0161  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Vasodilator-stimulated phosphoprotein (VASP) Ena/VASP family P50552

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060