Details of the Target

General Information of Target

Target ID LDTP17006
Target Name Epithelial cell-transforming sequence 2 oncogene-like (ECT2L)
Gene Name ECT2L
Gene ID 345930
Synonyms
C6orf91; LFDH; Epithelial cell-transforming sequence 2 oncogene-like; Lung-specific F-box and DH domain-containing protein; Putative guanine nucleotide exchange factor LFDH
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MMAAKVVPMPPKPKQSFILRVPPDSKLGQDLLRDATNGPKTIHQLVLEHFLTFLPKPSLV
QPSQKVKETLVIMKDVSSSLQNRVHPRPLVKLLPKGVQKEQETVSLYLKANPEELVVFED
LNVFHCQEECVSLDPTQQLTSEKEDDSSVGEMMLLAVNGSNPEGEDPEREPVENEDYREK
SSDDDEMDSSLVSQQPPDNQEKERLNTSIPQKRKMRNLLVTIENDTPLEELSKYVDISII
ALTRNRRTRRWYTCPLCGKQFNESSYLISHQRTHTGEKPYDCNHCGKSFNHKTNLNKHER
IHTGEKPYSCSQCGKNFRQNSHRSRHEGIHIREKIFKCPECGKTFPKNEEFVLHLQSHEA
ERPYGCKKCGRRFGRLSNCTRHEKTHSACKTRKQK
Target Bioclass
Other
Function May act as a guanine nucleotide exchange factor (GEF).
Uniprot ID
Q008S8
Ensemble ID
ENST00000367682.6
HGNC ID
HGNC:21118

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C375(0.00); C93(0.00); C42(0.00); C51(0.00)  LDD0161  [1]

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060