Details of the Target

General Information of Target

Target ID LDTP16988
Target Name Zinc finger CCCH domain-containing protein 6 (ZC3H6)
Gene Name ZC3H6
Gene ID 376940
Synonyms
KIAA2035; ZC3HDC6; Zinc finger CCCH domain-containing protein 6
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MKIPVLPAVVLLSLLVLHSAQGATLGGPEEESTIENYASRPEAFNTPFLNIDKLRSAFKA
DEFLNWHALFESIKRKLPFLNWDAFPKLKGLRSATPDAQ
Target Bioclass
Transcription factor
Uniprot ID
P61129
Ensemble ID
ENST00000409871.6
HGNC ID
HGNC:24762

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C339(0.90); C345(0.90)  LDD0078  [1]
IA-alkyne
 Probe Info  		C179(0.00); C159(0.00); C11(0.00)  LDD0161  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0020  ARS-1620 HCC44 C339(0.90); C345(0.90)  LDD0078  [1]
 LDCM0022  KB02 HCT 116 C339(2.27); C345(2.27)  LDD0080  [1]
 LDCM0023  KB03 HCT 116 C339(1.83); C345(1.83)  LDD0081  [1]
 LDCM0024  KB05 HCT 116 C339(1.69); C345(1.69)  LDD0082  [1]

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060