General Information of Target

Target ID LDTP16987
Target Name Keratinocyte differentiation-associated protein (KRTDAP)
Gene Name KRTDAP
Gene ID 388533
Synonyms
KDAP; Keratinocyte differentiation-associated protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGDWKVYISAVLRDQRIDDVAIVGHADNSCVWASRPGGLLAAISPQEVGVLTGPDRHTFL
QAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVGRAPRALLVLMGRRGVHGGI
LNKTVHELIRGLRMQGA
Target Bioclass
Other
Subcellular location
Secreted
Function May act as a soluble regulator of keratinocyte differentiation. May play an important role in embryonic skin morphogenesis.
Uniprot ID
P60985
Ensemble ID
ENST00000338897.4
HGNC ID
HGNC:16313

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
DU145 SNV: p.L91M .
MFE319 SNV: p.R75K .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info 
N.A.  LDD0161  [1]

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060