Details of the Target

General Information of Target

Target ID LDTP16977
Target Name Olfactory receptor 1D5 (OR1D5)
Gene Name OR1D5
Gene ID 8386
Synonyms
Olfactory receptor 1D5; Olfactory receptor 17-31; OR17-31
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MKIELSMQPWNPGYSSEGATAQETYTCPKMIEMEQAEAQLAELDLLASMFPGENELIVND
QLAVAELKDCIEKKTMEGRSSKVYFTINMNLDVSDEKMAMFSLACILPFKYPAVLPEITV
RSVLLSRSQQTQLNTDLTAFLQKHCHGDVCILNATEWVREHASGYVSRDTSSSPTTGSTV
QSVDLIFTRLWIYSHHIYNKCKRKNILEWAKELSLSGFSMPGKPGVVCVEGPQSACEEFW
SRLRKLNWKRILIRHREDIPFDGTNDETERQRKFSIFEEKVFSVNGARGNHMDFGQLYQF
LNTKGCGDVFQMFFGVEGQ
Target Bioclass
GPCR
Family
G-protein coupled receptor 1 family
Subcellular location
Cell membrane
Function Odorant receptor.
Uniprot ID
P58170
Ensemble ID
ENST00000575751.1
HGNC ID
HGNC:8186

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C169(1.74)  LDD3334  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 JURL-MK1 C169(2.09)  LDD2410  [1]
 LDCM0023  KB03 Hs 936.T C169(2.02)  LDD2780  [1]
 LDCM0024  KB05 MOLM-16 C169(1.74)  LDD3334  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840