General Information of Target

Target ID LDTP16961
Target Name Melanoma-associated antigen 9 (MAGEA9; MAGEA9B)
Gene Name MAGEA9; MAGEA9B
Gene ID 4108
Synonyms
MAGE9; MAGEA9A; Melanoma-associated antigen 9; Cancer/testis antigen 1.9; CT1.9; MAGE-9 antigen
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSLEQKSQHCKPEEGLDTQEEALGLVGVQAATTEEQEAVSSSSPLVPGTLGEVPAAGSPG
PLKSPQGASAIPTAIDFTLWRQSIKGSSNQEEEGPSTSPDPESVFRAALSKKVADLIHFL
LLKY
Target Bioclass
Other
Function Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.
Uniprot ID
P43362
Ensemble ID
ENST00000243314.5
HGNC ID
HGNC:6807

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C299(1.07)  LDD3351  [1]
IA-alkyne
 Probe Info 
N.A.  LDD2241  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 CAL-120 C299(0.85)  LDD2284  [1]
 LDCM0023  KB03 HCC1806 C299(2.47)  LDD2758  [1]
 LDCM0024  KB05 NCI-H196 C299(1.07)  LDD3351  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853