Details of the Target

General Information of Target

Target ID LDTP16951
Target Name Gamma-crystallin A (CRYGA)
Gene Name CRYGA
Gene ID 1418
Synonyms
CRYG1; Gamma-crystallin A; Gamma-A-crystallin; Gamma-crystallin 5
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGPLSAPPCTEHIKWKGLLVTASLLNFWNLPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ
NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY
TLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVILTCDPETPDTSYQW
WMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIRNSGSASRSDPVTLNLLHGPD
LPRIHPSYTNYRSGDNLYLSCFANSNPPAQYSWTINGKFQQSGQNLFIPQITTKHSGLYV
CSVRNSATGEESSTSLTVKVSASTRIGLLPLLNPT
Target Bioclass
Other
Family
Beta/gamma-crystallin family
Function Crystallins are the dominant structural components of the vertebrate eye lens.
Uniprot ID
P11844
Ensemble ID
ENST00000304502.5
HGNC ID
HGNC:2408

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C81(0.00); C62(0.00); C173(0.00); C160(0.00)  LDD0161  [1]

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060