Details of the Target
General Information of Target
| Target ID | LDTP16916 | |||||
|---|---|---|---|---|---|---|
| Target Name | Peptidyl-prolyl cis-trans isomerase A-like 4F (PPIAL4F) | |||||
| Gene Name | PPIAL4F | |||||
| Gene ID | 728945 | |||||
| Synonyms |
Peptidyl-prolyl cis-trans isomerase A-like 4F; PPIase A-like 4F; EC 5.2.1.8 |
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| 3D Structure | ||||||
| Sequence |
MDPGNHSSVTESILAGLSEQPELQLRLFLLFLGICVVTVVGNLGMITLIGLSSHLHTPMY
YFLSSLSFIDFCHSTVITPKMLVNFATEKNIISYPECMAQLYLFSIFAIAECHMLAAMAY DCYVAICSPLLYNVIMSYHHCFWLTVGVYILGILGSTIHTSFMLRLFLCKTNVINHYFCD LFPLLGLSCSSTYINELLVLVLSAFNILMPALTILASYIFIIASILRIHSTEGRSKAFST CSSHILAVAVFFGSAAFMYLQPSSVSSMDQRKVSSVFYTTIVPMLNPLIYSLRNKDVKLA VKKILHQTAC |
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| Target Bioclass |
Enzyme
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| Family |
Cyclophilin-type PPIase family, PPIase A subfamily
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| Subcellular location |
Cytoplasm
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| Function | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
AZ-9 Probe Info |
 |
E120(1.12) | LDD2208 | [1] | |
|
IA-alkyne Probe Info |
 |
C62(1.38) | LDD2207 | [2] | |
|
NAIA_5 Probe Info |
 |
N.A. | LDD2224 | [3] | |
Competitor(s) Related to This Target
References