Details of the Target

General Information of Target

Target ID LDTP16907
Target Name Testis-specific Y-encoded protein 10 (TSPY10)
Gene Name TSPY10
Gene ID 100289087
Synonyms
Testis-specific Y-encoded protein 10
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MRPEGSLTYWVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALG
EEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESALEELLAVQVELE
PVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDM
LSYMVSLEVEEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYLD
YEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTET
SGDSQLLS
Target Bioclass
Other
Family
Nucleosome assembly protein (NAP) family
Subcellular location
Cytoplasm
Function May be involved in sperm differentiation and proliferation.
Uniprot ID
P0CW01
Ensemble ID
ENST00000428845.6
HGNC ID
HGNC:37473

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C283(4.83)  LDD3364  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 A498 C283(1.57)  LDD2259  [1]
 LDCM0023  KB03 A498 C283(3.46)  LDD2676  [1]
 LDCM0024  KB05 NCI-N87 C283(4.83)  LDD3364  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840