General Information of Target

Target ID LDTP16899
Target Name Tripartite motif-containing protein 49C (TRIM49C)
Gene Name TRIM49C
Gene ID 642612
Synonyms
TRIM49L2; Tripartite motif-containing protein 49C; Tripartite motif-containing protein 49-like protein 2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MHSLEKVTFEDVAIDFTQEEWDMMDTSKRKLYRDVMLENISHLVSLGYQISKSYIILQLE
QGKELWREGRVFLQDQNPDRESALKKKHMISMHPIIRKDASTSMTMENSLILEDPFEYND
SGEDCTHSSTITQCLLTHSGKKPCVSKQCGKSLRNLLSPKPRKQIHTKGKSYQCNLCEKA
YTNCFYLRRHKMTHTGERPYACHLCGKAFTQCSHLRRHEKTHTGERPYKCHQCGKAFIQS
FNLRRHERTHLGQKCYECDKSGKAFSQSSGFRGNKIIHIGEKPHACLLCGKAFSLSSDLR
Target Bioclass
Enzyme
Uniprot ID
P0CI26
Ensemble ID
ENST00000448984.1
HGNC ID
HGNC:38877

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C104(1.47)  LDD2261  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 A673 C104(1.47)  LDD2261  [1]
 LDCM0023  KB03 SK-ES1 C104(1.27)  LDD3006  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840