General Information of Target

Target ID LDTP16894
Target Name Cryptic family protein 1B (CFC1B)
Gene Name CFC1B
Gene ID 653275
Synonyms
Cryptic family protein 1B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MHKARLRGHCARAGKSVRLASSGMTRRDPLTNKVALVTASTDWIGFAVAQRLAQDGAHVV
VSRRKQQNVDQAVATLQGEGLSMTGTVCHVGKMKDWERLVATAMKLHGVIDILSLSITNS
KRGLFWFTLLQTAEEAWDRNLDINGKALALMIKAVVPEMEKRGGGSVGFLASVAAFRPLP
GFSPYNVSKTALLGLNKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETL
RIRRLGEPEDSLGIVSFLCSEDASYLTGETVMVGGGTPSRL
Target Bioclass
Other
Family
EGF-CFC (Cripto-1/FRL1/Cryptic) family
Subcellular location
Secreted
Uniprot ID
P0CG36
Ensemble ID
ENST00000281882.8
HGNC ID
HGNC:33983

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C114(3.08)  LDD2243  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 22RV1 C114(3.08)  LDD2243  [1]
 LDCM0023  KB03 22RV1 C114(5.17)  LDD2660  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840