General Information of Target

Target ID LDTP16847
Target Name Neuronal pentraxin receptor (NPTXR)
Gene Name NPTXR
Gene ID 23467
Synonyms
Neuronal pentraxin receptor
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPQNEYIELHRKRYGYRLDYHEKKRKKESREAHERSKKAKKMIGLKAKLYHKQRHAEKIQ
MKKTIKMHEKRNTKQKNDEKTPQGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVP
LPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCFVGDGFTRKPPKYERFIRPMGLRFKK
AHVTHPELKATFCLPILGVKKNPSSPLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGK
YAQVTNNPENDGCINAVLLV
Target Bioclass
Other
Subcellular location
Membrane
Function May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
Uniprot ID
O95502
Ensemble ID
ENST00000333039.4
HGNC ID
HGNC:7954

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
ONAyne
 Probe Info 
K251(10.00)  LDD0275  [1]

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270