Details of the Target

General Information of Target

Target ID LDTP16831
Target Name Secretagogin (SCGN)
Gene Name SCGN
Gene ID 10590
Synonyms
SECRET; Secretagogin
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MNWENESSPKEFILLGFSDRAWLQMPLFVVLLISYTITIFGNVSIMMVCILDPKLHTPMY
FFLTNLSILDLCYTTTTVPHMLVNIGCNKKTISYAGCVAHLIIFLALGATECLLLAVMSF
DRYVAVCRPLHYVVIMNYWFCLRMAAFSWLIGFGNSVLQSSLTLNMPRCGHQEVDHFFCE
VPALLKLSCADTKPIEAELFFFSVLILLIPVTLILISYGFIAQAVLKIRSAEGRQKAFGT
CGSHMIVVSLFYGTAIYMYLQPPSSTSKDWGKMVSLFYGIITSMLNSLIYSLRNKDMKEA
FKRLMPRIFFCKK
Target Bioclass
Other
Subcellular location
Cytoplasm
Uniprot ID
O76038
Ensemble ID
ENST00000377961.3
HGNC ID
HGNC:16941

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C269(13.39)  LDD3340  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 Calu-1 C269(1.43)  LDD2292  [1]
 LDCM0023  KB03 Calu-1 C269(1.55)  LDD2709  [1]
 LDCM0024  KB05 NB1 C269(13.39)  LDD3340  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840