General Information of Target

Target ID LDTP16795
Target Name LYR motif-containing protein 1 (LYRM1)
Gene Name LYRM1
Gene ID 57149
Synonyms
LYR motif-containing protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MELGHGAGTTTFTRAHLNDKEGQQDLDPWKAAYSSLDTSKFKNQGLSSPQPLPLGASAQG
SSLGQCHLKEIPPPPPTAASRDSLGMDPQSRSLKNAGSRSSSRENRATSGEGAQPCQGTD
DGPSLGAQDQRSTPTNQKGSIIPNNIRHKFGSNVVDQLVSEEQAQKAIDEVFEGQKRASS
WPSRTQNPVEISSVFSDYYDLGYNMRSNLFRGAAEETKSLMKASYTPEVIEKSVRDLEHW
HGRKTDDLGRWHQKNAMNLNLQKALEEKYGENSKSKSSKY
Target Bioclass
Other
Family
Complex I LYR family
Subcellular location
Nucleus
Function May promote cell proliferation and inhibition of apoptosis of preadipocytes.
Uniprot ID
O43325
Ensemble ID
ENST00000219168.8
HGNC ID
HGNC:25074

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
YN-1
 Probe Info 
N.A.  LDD0447  [1]

References

1 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.