General Information of Target

Target ID LDTP16779
Target Name High mobility group nucleosome-binding domain-containing protein 4 (HMGN4)
Gene Name HMGN4
Gene ID 10473
Synonyms
HMG17L3; NHC; High mobility group nucleosome-binding domain-containing protein 4; Non-histone chromosomal protein HMG-17-like 3; Non-histone chromosomal protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPRAFLVRSRRPQPPNWGHLPDQLRGDAYIPDCSSLGGPPAQQSSSVRDPWTAQPTQGNL
TSAPRGPGTLGCPLCPKAFPLQRMLTRHLKCHSPVRRHLCRCCGKGFHDAFDLKRHMRTH
TGIRPFRCSACGKAFTQRCSLEAHLAKVHGQPASYAYRERREKLHVCEDCGFTSSRPDTY
AQHRALHRAA
Target Bioclass
Other
Family
HMGN family
Subcellular location
Nucleus
Uniprot ID
O00479
Ensemble ID
ENST00000377575.3
HGNC ID
HGNC:4989

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info 
K31(10.00)  LDD0277  [1]
IA-alkyne
 Probe Info 
C128(0.00); C468(0.00); C223(0.00); C52(0.00)  LDD0161  [2]
NHS
 Probe Info 
N.A.  LDD0010  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Telomeric repeat-binding factor 2-interacting protein 1 (TERF2IP) RAP1 family Q9NYB0

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
3 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764