Details of the Target

General Information of Target

Target ID LDTP16738
Target Name Apical junction component 1 homolog (AJM1)
Gene Name AJM1
Gene ID 389813
Synonyms
C9orf172; Apical junction component 1 homolog
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MIQQEEIRKLEEEKKQLEGEIIDFYKMKAASEALQTQLSTDTKKDKHPDPYEFLLLRKIK
HPGFNEELSPC
Target Bioclass
Other
Subcellular location
Apical cell membrane
Function May be involved in the control of adherens junction integrity.
Uniprot ID
C9J069
Ensemble ID
ENST00000436881.3
HGNC ID
HGNC:37284

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C726(2.27)  LDD2469  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 MGG123 C726(2.27)  LDD2469  [1]
 LDCM0023  KB03 MGG123 C726(3.49)  LDD2886  [1]
 LDCM0024  KB05 MGG123 C726(3.04)  LDD3303  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840