Details of the Target

General Information of Target

Target ID LDTP16695
Target Name Putative PDZ domain-containing protein PDZK1P1 (PDZK1P1)
Gene Name PDZK1P1
Synonyms
PDZK1P2; Putative PDZ domain-containing protein PDZK1P1; PDZ domain-containing 1 pseudogene 1; PDZ domain-containing 1 pseudogene 2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MTHCCSPCCQPTCCRTTCWKPTTVTTCSSTPCCQPSCCVSSCCQPCCHPTCCQNTCCRTT
CCQPTCVTSCCQPSCCSTPCCQPICCGSSCCGQTSCGSSCCQPSSCAPIYCRRTCYHPTS
VYLPGCLNQSCGSSCCQPCCRPACCETTCCRTTCFQPTCVTSCCQPACC
Target Bioclass
Other
Family
NHER family
Uniprot ID
A8MUH7
HGNC ID
HGNC:31974

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Probe 1
 Probe Info  		Y343(9.24); Y345(57.35)  LDD3495  [1]
DBIA
 Probe Info  		C455(1.05)  LDD2268  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 BRX211 C455(1.05)  LDD2268  [2]
 LDCM0023  KB03 BRX211 C455(1.05)  LDD2685  [2]
 LDCM0024  KB05 BRX211 C455(1.33)  LDD3102  [2]

References

1 An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840