Details of the Target

General Information of Target

Target ID LDTP16686
Target Name Ankyrin repeat domain-containing protein 36A (ANKRD36)
Gene Name ANKRD36
Gene ID 375248
Synonyms
ANKRD36A; KIAA1641; Ankyrin repeat domain-containing protein 36A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MFHGTVTEELTSHEEWSHYNENIREGQKDFVFVKFNGLHLKSMENLQSCISLRVCIFSNN
FITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNLKLLYLHDNGFAKLKNICVLSA
CPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWHLPERFKACNHR
LFFNFCPALRKGTTYEEEINNIKHITSKINAILAHNSPVLIVQRWIRGFLVRKNLSPVFF
HKKKQQEKIIRGYEAKWIYITKGYEDKLLKDLFFKPETNIKGKLAYWKHNIYYPVDLKNS
SEHRKHVSSILCELKPKDLGMKSKTSRHLIQKGQESEDEIVDEKLDTSFRISVFKLPIYT
SGSLKNNAVLREKKQHFFPAYPQPIYTTHPKPIIKKDIRLERSMKEFFAPQRAGMKLRTF
SDIDKYYTEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQ
NSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEK
NEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAFEKACERL
QDAKTKVAIVKTNLDFKVPNGLIK
Target Bioclass
Other
Family
ANKRD36 family
Uniprot ID
A6QL64
Ensemble ID
ENST00000420699.9
HGNC ID
HGNC:24079

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CAL120 SNV: p.N599D; p.D1150Y .
COLO829 SNV: p.S1120C .
DU145 SNV: p.E763Ter .
EOL1 Substitution: p.R405S .
G415 Insertion: p.L1723DfsTer8 .
GAMG Substitution: p.R405S .
HCT116 SNV: p.A323S .
ICC10 Insertion: p.P925TfsTer8 .
KMS27 SNV: p.S1052Y .
KO52 Deletion: p.V319_S320del .
KU1919 Substitution: p.R405S .
KYM1 Substitution: p.R405S .
LS180 Deletion: p.K924NfsTer17 .
MKN45 SNV: p.V953L .
NCIH2172 SNV: p.A1099S .
OSRC2 SNV: p.R942G .
OV90 Substitution: p.R405S .
RL952 Substitution: p.R405S .
RVH421 Substitution: p.R405S .
SAOS2 SNV: p.T1168I .
SKMEL3 Substitution: p.P1126Ter .
SKN Substitution: p.P27Y .
SNU423 Substitution: p.R405S .
SUDHL6 SNV: p.Y137F .
TOV21G SNV: p.A72T .
U87MG Substitution: p.R405S .
WM115 SNV: p.G777Ter .
WM2664 SNV: p.G777Ter .
YSCCC SNV: p.D694N .
ZR751 Substitution: p.R405S .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		N.A.  LDD0161  [1]

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060