Details of the Target
General Information of Target
| Target ID | LDTP16632 | |||||
|---|---|---|---|---|---|---|
| Target Name | Putative neutrophil cytosol factor 1B (NCF1B) | |||||
| Gene Name | NCF1B | |||||
| Synonyms |
SH3PXD1B; Putative neutrophil cytosol factor 1B; NCF-1B; Putative SH3 and PX domain-containing protein 1B |
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| 3D Structure | ||||||
| Sequence |
MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKTSE
KPNFNTNLVLKKLSSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEH MAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETSTFHSLKDYVSVRKRIITI QYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHMPD VVLLQDVRNVSARTDLAQMQKPQPVNPELTSWCITGVLDMLNNFRVDSALSTEMIPCYIS LSEDVRYVIFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKHYWEVDVTLSSNWILGVCRDS RTADANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGRVGVFLDYDNGSVSFF DVSKGSLIYGFPPSSFSSPLRPFFCFGCT |
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| Target Bioclass |
Other
|
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| Subcellular location |
Cytoplasm
|
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| Function | May be required for activation of the latent NADPH oxidase (necessary for superoxide production). | |||||
| Uniprot ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C87(2.00); C197(2.62) | LDD3333 | [1] | |
Competitor(s) Related to This Target