General Information of Target

Target ID LDTP16082
Target Name Sperm protein associated with the nucleus on the X chromosome A (SPANXA1; SPANXA2)
Gene Name SPANXA1; SPANXA2
Gene ID 30014
Synonyms
SPANXA; Sperm protein associated with the nucleus on the X chromosome A; Cancer/testis antigen 11.1; CT11.1; Nuclear-associated protein SPAN-Xa; SPAN-X; SPANX-A; SPANX family member A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGQQSSVRRLKRSVPCESNEANEANEANKTMPETPTGDSDPQPAPKKMKTSESSTILVVR
YRRNVKRTSPEELLNDHARENRINPDQMEEEEFIEITTERPKK
Target Bioclass
Other
Family
SPAN-X family
Subcellular location
Cytoplasm
Uniprot ID
Q9NS26
Ensemble ID
ENST00000370518.4
HGNC ID
HGNC:11218

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C16(1.43)  LDD3462  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 TCCSUP C16(1.95)  LDD2631  [1]
 LDCM0023  KB03 RT-112 C16(2.06)  LDD2995  [1]
 LDCM0024  KB05 T24 C16(1.43)  LDD3462  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840