Details of the Target
General Information of Target
| Target ID | LDTP16033 | |||||
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| Target Name | Putative N-acetylated-alpha-linked acidic dipeptidase (FOLH1B) | |||||
| Gene Name | FOLH1B | |||||
| Synonyms |
PSMAL; Putative N-acetylated-alpha-linked acidic dipeptidase; NAALADase; EC 3.4.-.-; Cell growth-inhibiting gene 26 protein; Prostate-specific membrane antigen-like protein; Putative folate hydrolase 1B
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| 3D Structure | ||||||
| Sequence |
MELALRRSPVPRWLLLLPLLLGLNAGAVIDWPTEEGKEVWDYVTVRKDAYMFWWLYYATN
SCKNFSELPLVMWLQGGPGGSSTGFGNFEEIGPLDSDLKPRKTTWLQAASLLFVDNPVGT GFSYVNGSGAYAKDLAMVASDMMVLLKTFFSCHKEFQTVPFYIFSESYGGKMAAGIGLEL YKAIQRGTIKCNFAGVALGDSWISPVDSVLSWGPYLYSMSLLEDKGLAEVSKVAEQVLNA VNKGLYREATELWGKAEMIIEQNTDGVNFYNILTKSTPTSTMESSLEFTQSHLVCLCQRH VRHLQRDALSQLMNGPIRKKLKIIPEDQSWGGQATNVFVNMEEDFMKPVISIVDELLEAG INVTVYNGQLDLIVDTMGQEAWVRKLKWPELPKFSQLKWKALYSDPKSLETSAFVKSYKN LAFYWILKAGHMVPSDQGDMALKMMRLVTQQE |
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| Target Bioclass |
Enzyme
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| Family |
Peptidase M28 family, M28B subfamily
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| Subcellular location |
Cytoplasm
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| Function | Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity.; Exhibits a dipeptidyl-peptidase IV type activity. | |||||
| Uniprot ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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DBIA Probe Info |
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C597(1.84) | LDD3486 | [1] | |
Competitor(s) Related to This Target