Details of the Target

General Information of Target

Target ID LDTP16016
Target Name Zinc finger matrin-type protein 4 (ZMAT4)
Gene Name ZMAT4
Gene ID 79698
Synonyms
Zinc finger matrin-type protein 4
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLKAKILFVGPCESGKTVLANFLTESSDITEYSPTQGVRILEFENPHVTSNNKGTGCEFE
LWDCGGDAKFESCWPALMKDAHGVVIVFNADIPSHRKEMEMWYSCFVQQPSLQDTQCMLI
AHHKPGSGDDKGSLSLSPPLNKLKLVHSNLEDDPEEIRMEFIKYLKSIINSMSESRDREE
MSIMT
Target Bioclass
Other
Subcellular location
Nucleus
Uniprot ID
Q9H898
Ensemble ID
ENST00000297737.11
HGNC ID
HGNC:25844

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
SF295 SNV: p.K171N .
SW1116 SNV: p.S62Ter .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C55(2.38)  LDD3344  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 HuP-T3 C55(3.63)  LDD2377  [1]
 LDCM0023  KB03 HuP-T3 C55(2.87)  LDD2794  [1]
 LDCM0024  KB05 NCI-H146 C55(2.38)  LDD3344  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840