Details of the Target
General Information of Target
| Target ID | LDTP15990 | |||||
|---|---|---|---|---|---|---|
| Target Name | GPI mannosyltransferase 1 (PIGM) | |||||
| Gene Name | PIGM | |||||
| Gene ID | 93183 | |||||
| Synonyms |
GPI mannosyltransferase 1; EC 2.4.1.-; GPI mannosyltransferase I; GPI-MT-I; Phosphatidylinositol-glycan biosynthesis class M protein; PIG-M |
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| 3D Structure | ||||||
| Sequence |
MDFIFHEKQEGFLCAQHCLNNLLQGEYFSPVELASIAHQLDEEERMRMAEGGVTSEEYLA
FLQQPSENMDDTGFFSIQVISNALKFWGLEIIHFNNPEYQKLGIDPINERSFICNYKQHW FTIRKFGKHWFNLNSLLAGPELISDTCLANFLARLQQQAYSVFVVKGDLPDCEADQLLQI ISVEEMDTPKLNGKKLVKQKEHRVYKTVLEKVSEESDESGTSDQDEEDFQRALELSRQET NREDEHLRSTIELSMQGSSGNTSQDLPKTSCVTPASEQPKKIKEDYFEKHQQEQKQQQQQ SDLPGHSSYLHERPTTSSRAIESDLSDDISEGTVQAAVDTILEIMRKNLKIKGEK |
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| Target Bioclass |
Enzyme
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| Family |
PIGM family
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| Subcellular location |
Endoplasmic reticulum membrane
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| Function | Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
PAL-AfBPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
OEA-DA Probe Info |
 |
20.00 | LDD0046 | [1] | |