Details of the Target

General Information of Target

Target ID LDTP15901
Target Name Zinc finger protein 471 (ZNF471)
Gene Name ZNF471
Gene ID 57573
Synonyms
ERP1; KIAA1396; Zinc finger protein 471; EZFIT-related protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDNQAERESEAGVGLQRDEDDAPLCEDVELQDGDLSPEEKIFLREFPRLKEDLKGNIDKL
RALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLSTAGQGLATAA
GVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKIIYNLRNTLKY
AKKNVRAFWKLRANPRLANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNARVLGGVM
SAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYKSLQQKVRSRA
RGVGKDLTGTCETEAYWKELREHVWMWLWLCVCLCVCVYVQFT
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q9BX82
Ensemble ID
ENST00000308031.10
HGNC ID
HGNC:23226

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AN3CA SNV: p.F524S .
HCC1937 SNV: p.H364L .
HT115 SNV: p.R310K .
HUH1 SNV: p.E266V .
IGR1 SNV: p.H228Y .
MCC13 SNV: p.G389R .
OPM2 SNV: p.E145Ter .
REH Deletion: p.E263VfsTer125 .
SUIT2 SNV: p.R363L .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HHS-465
 Probe Info  		K288(0.00); K291(0.00); Y290(0.00)  LDD2240  [1]

References

1 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010