General Information of Target

Target ID LDTP15855
Target Name PH and SEC7 domain-containing protein 2 (PSD2)
Gene Name PSD2
Gene ID 84249
Synonyms
EFA6C; PH and SEC7 domain-containing protein 2; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 C; Exchange factor for ARF6 C; Pleckstrin homology and SEC7 domain-containing protein 2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MFLTALLWRGRIPGRQWIGKHRRPRFVSLRAKQNMIRRLEIEAENHYWLSMPYMTREQER
GHAAVRRREAFEAIKAAATSKFPPHRFIADQLDHLNVTKKWS
Target Bioclass
Other
Family
PSD family
Subcellular location
Cell membrane
Uniprot ID
Q9BQI7
Ensemble ID
ENST00000274710.4
HGNC ID
HGNC:19092

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C679(1.10)  LDD2279  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 BT-549 C679(1.10)  LDD2279  [1]
 LDCM0023  KB03 MCF-7 C679(2.19)  LDD2869  [1]
 LDCM0024  KB05 MCF-7 C679(2.56)  LDD3286  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840