Details of the Target

General Information of Target

Target ID LDTP15828
Target Name Zinc finger protein 347 (ZNF347)
Gene Name ZNF347
Gene ID 84671
Synonyms
ZNF1111; Zinc finger protein 347; Zinc finger protein 1111
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLSSFLSPQNGTWADTFSLLLALAVALYLGYYWACVLQRPRLVAGPQFLAFLEPHCSITT
ETFYPTLWCFEGRLQSIFQVLLQSQPLVLYQSDILQTPDGGQLLLDWAKQPDSSQDPDPT
TQPIVLLLPGITGSSQETYVLHLVNQALRDGYQAVVFNNRGCRGEELRTHRAFCASNTED
LETVVNHIKHRYPQAPLLAVGISFGGILVLNHLAQARQAAGLVAALTLSACWDSFETTRS
LETPLNSLLFNQPLTAGLCQLVERNRKVIEKVVDIDFVLQARTIRQFDERYTSVAFGYQD
CVTYYKAASPRTKIDAIRIPVLYLSAADDPFSPVCALPIQAAQHSPYVALLITARGGHIG
FLEGLLPWQHWYMSRLLHQYAKAIFQDPEGLPDLRALLPSEDRNS
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q96SE7
Ensemble ID
ENST00000334197.12
HGNC ID
HGNC:16447

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AGS SNV: p.N43T .
DU145 SNV: p.L556I .
HCC15 SNV: p.R30G .
HGC27 SNV: p.E211Q .
HT115 SNV: p.A384D .
KMCH1 Deletion: p.K262NfsTer43 .
LNCaP clone FGC SNV: p.L197F .
LS180 Deletion: p.K399NfsTer46 .
MEWO SNV: p.N418H .
NALM6 SNV: p.R385C .
NCIH1792 SNV: p.R132M .
RKO Deletion: p.K735NfsTer71 .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HHS-465
 Probe Info  		K343(0.00); K346(0.00); Y345(0.00)  LDD2240  [1]

References

1 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010