Details of the Target
General Information of Target
| Target ID | LDTP15779 | |||||
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| Target Name | Leucine-rich repeat and guanylate kinase domain-containing protein (LRGUK) |
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| Gene Name | LRGUK | |||||
| Gene ID | 136332 | |||||
| Synonyms |
Leucine-rich repeat and guanylate kinase domain-containing protein |
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| 3D Structure | ||||||
| Sequence |
MMEESGIETTPPGTPPPNPAGLAATAMSSTPVPLAATSSFSSPNVSSMESFPPLAYSTPQ
PPLPPVRPSAPLPFVPPPAVPSVPPLVTSMPPPVSPSTAAAFGNPPVSHFPPSTSAPNTL LPAPPSGPPISGFSVGSTYDITRGHAGRAPQTPLMPSFSAPSGTGLLPTPITQQASLTSL AQGTGTTSAITFPEEQEDPRITRGQDEASAGGIWGFIKGVAGNPMVKSVLDKTKHSVESM ITTLDPGMAPYIKSGGELDIVVTSNKEVKVAAVRDAFQEVFGLAVVVGEAGQSNIAPQPV GYAAGLKGAQERIDSLRRTGVIHEKQTAVSVENFIAELLPDKWFDIGCLVVEDPVHGIHL ETFTQATPVPLEFVQQAQSLTPQDYNLRWSGLLVTVGEVLEKSLLNVSRTDWHMAFTGMS RRQMIYSAARAIAGMYKQRLPPRTV |
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| Target Bioclass |
Enzyme
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| Subcellular location |
Cytoplasmic vesicle, secretory vesicle, acrosome
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| Function | Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
PAL-AfBPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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STS-1 Probe Info |
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N.A. | LDD0136 | [1] | |