General Information of Target

Target ID LDTP15774
Target Name Apolipoprotein L domain-containing protein 1 (APOLD1)
Gene Name APOLD1
Gene ID 81575
Synonyms
VERGE; Apolipoprotein L domain-containing protein 1; Vascular early response gene protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGAGVGVAGCTRGHRNWVPSQLPPREIKAGVSLAVVTEFAWVLAPRPKRATASALGTESP
RFLDRPDFFDYPDSDQARLLAVAQFIGEKPIVFINSGSSPGLFHHILVGLLVVAFFFLLF
QFCTHINFQKGA
Target Bioclass
Other
Family
Apolipoprotein L family
Subcellular location
Cell membrane
Function May be involved in angiogenesis. May play a role in activity-dependent changes of brain vasculature. May affect blood-brain permeability.
Uniprot ID
Q96LR9
Ensemble ID
ENST00000326765.10
HGNC ID
HGNC:25268

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C258(2.87)  LDD2329  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 G-361 C258(2.87)  LDD2329  [1]
 LDCM0023  KB03 G-361 C258(4.97)  LDD2746  [1]
 LDCM0024  KB05 G-361 C258(3.96)  LDD3163  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840