Details of the Target

General Information of Target

Target ID LDTP15773
Target Name Fertilization-influencing membrane protein (FIMP)
Gene Name FIMP
Gene ID 146378
Synonyms
C16orf92; Fertilization-influencing membrane protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MTREQYILATQQNNLPRTENAQLYPVGIYGWRKRCLYFFVLLLLVTMIVNLAMTIWILKV
MNFTVDGMGNLRVTKKGIRLEGISEFLLPLYVKEIHSRKDSPLVLQSDRNVTVNARNHMG
QLTGQLTIGADAVEAQCKRFEVRASEDGRVLFSADEDEITIGAEKLKVTGTEGAVFGHSV
ETPHIRAEPSQDLRLESPTRSLIMEAPRGVQVSAAAGDFKATCRKELHLQSTEGEIFLNA
ETIKLGNLPTGSFSSSSPSSSSSRQTVYELCVCPNGKLYLSPAGVGSTCQSSSNICLWS
Target Bioclass
Other
Subcellular location
Cell membrane
Function May play a role in sperm-oocyte fusion during fertilization.
Uniprot ID
Q96LL3
Ensemble ID
ENST00000300575.6
HGNC ID
HGNC:26346

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		N.A.  LDD0032  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 (PLPP6) PA-phosphatase related phosphoesterase family Q8IY26
Pepsin A-4 (PGA4) Peptidase A1 family P0DJD7
Transporter and channel
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Novel acetylcholine receptor chaperone (TMEM35A) DoxX family Q53FP2
Statherin (STATH) Histatin/statherin family P02808
Myeloid-associated differentiation marker (MYADM) MAL family Q96S97
Cytokine and receptor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
C-X-C motif chemokine 9 (CXCL9) Intercrine alpha (chemokine CxC) family Q07325
Other
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Low-density lipoprotein receptor-related protein 10 (LRP10) LDLR family Q7Z4F1
Neuronal vesicle trafficking-associated protein 1 (NSG1) NSG family P42857
Reticulophagy regulator 3 (RETREG3) RETREG family Q86VR2
Vesicle-trafficking protein SEC22a (SEC22A) Synaptobrevin family Q96IW7

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060