Details of the Target
General Information of Target
| Target ID | LDTP15768 | |||||
|---|---|---|---|---|---|---|
| Target Name | Rho-related GTP-binding protein RhoV (RHOV) | |||||
| Gene Name | RHOV | |||||
| Gene ID | 171177 | |||||
| Synonyms |
ARHV; WRCH2; Rho-related GTP-binding protein RhoV; CDC42-like GTPase 2; GTP-binding protein-like 2; Rho GTPase-like protein ARHV; Wnt-1 responsive Cdc42 homolog 2; WRCH-2 |
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| 3D Structure | ||||||
| Sequence |
MALAALMIALGSLGLHTWQAQAVPILPLGLAPDTFDDTYVGCAEEMEEKAAPLLKEEMAH
HALLRESWEAAQETWEDKRRGLTLPPGFKAQNGIAIMVYTNSSNTLYWELNQAVRTGGGS RELYMRHFPFKALHFYLIRALQLLRGSGGCSRGPGEVVFRGVGSLRFEPKRLGDSVRLGQ FASSSLDKAVAHRFGNATLFSLTTCFGAPIQAFSVFPKEREVLIPPHEVFLVTRFSQDGA QSLVTLWSYNQTCSHFNCAYLGGEKRRGCVSAPGALGTGDLHMTKRHLQQP |
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| Target Bioclass |
Enzyme
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| Family |
Small GTPase superfamily, Rho family
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| Subcellular location |
Cell membrane
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| Function | Plays a role in the control of the actin cytoskeleton via activation of the JNK pathway. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C52(2.11) | LDD2243 | [1] | |
Competitor(s) Related to This Target