Details of the Target

General Information of Target

Target ID LDTP15642
Target Name Prostate and testis expressed protein 1 (PATE1)
Gene Name PATE1
Gene ID 160065
Synonyms
PATE; Prostate and testis expressed protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPRLSLLLPLLLLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGISAL
DECGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAGAAPEGTGLCVCAQRGTVCGSDGR
SYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRA
VPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGV
YQCHAANMVGEAESHSTVTVLDLSKYRSFHFPAPDDRM
Target Bioclass
Other
Family
PATE family
Subcellular location
Secreted
Uniprot ID
Q8WXA2
Ensemble ID
ENST00000305738.10
HGNC ID
HGNC:24664

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
NCIH446 SNV: p.D120E .
WM115 SNV: p.P41S .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
TFBX
 Probe Info  		N.A.  LDD0148  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transcription factor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Proto-oncogene c-Rel (REL) . Q04864
Transcription factor 4 (TCF4) . P15884
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein INCA1 (INCA1) INCA family Q0VD86

References

1 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255