Details of the Target

General Information of Target

Target ID LDTP15639
Target Name GRB2-associated-binding protein 3 (GAB3)
Gene Name GAB3
Gene ID 139716
Synonyms
GRB2-associated-binding protein 3; GRB2-associated binder 3; Growth factor receptor bound protein 2-associated protein 3
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MPTDHEEPCGPSHKSFCLNGGLCYVIPTIPSPFCRCVENYTGARCEEVFLPGSSIQTKSN
LFEAFVALAVLVTLIIGAFYFLCRKGHFQRASSVQYDINLVETSSTSAHHSHEQH
Target Bioclass
Other
Family
GAB family
Uniprot ID
Q8WWW8
Ensemble ID
ENST00000369568.8
HGNC ID
HGNC:17515

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C336(7.47)  LDD1705  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0024  KB05 T cell C336(7.47)  LDD1705  [1]

References

1 An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.