Details of the Target

General Information of Target

Target ID LDTP15612
Target Name Suppressor of tumorigenicity 7 protein-like (ST7L)
Gene Name ST7L
Gene ID 54879
Synonyms
ST7R; Suppressor of tumorigenicity 7 protein-like; ST7-related protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
Target Bioclass
Other
Family
ST7 family
Subcellular location
Membrane
Uniprot ID
Q8TDW4
Ensemble ID
ENST00000343210.11
HGNC ID
HGNC:18441

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
22RV1 SNV: p.P505T .
DOTC24510 SNV: p.Q210P .
IPC298 SNV: p.R163K .
MCC13 SNV: p.L417Ter .
MCC26 SNV: p.R376K .
WM115 SNV: p.T369P .
WM2664 SNV: p.T369P .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		N.A.  LDD2156  [1]

References

1 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019